Acute liver failure (ALF), also known as fulminant hepatic failure, is a rare manifestation of liver disease and constittes a medical emergency.
The syndrome arises from loss of hepatic parenchyma that may result from a variety of insults to the liver.
Despite advances in medical management and the availability of liver transplantation, mortality rates in patients with ALF remain substantial. It has been estimated that in the United States, 2000 deaths a year are attributable to ALF.
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